Vitamin B12 Deficiency and Type 2 Diabetes

Vitamin B12, also known as “cobalamin,” is a water-soluble essential nutrient required in our diet. When a nutrient is essential, it means so it should come from food we eat or supplemental kind, the body can not produce it internally.

You could be at greater risk of a vitamin B12 deficiency if you have type 2 diabetes. Vitamin B12 supports a healthy nervous system, brain and red blood cells and is needed only in tiny amounts (2.4 mcg/day).  

Vitamin B12 is found only in meat, fish, poultry, eggs, and dairy, which explains the reason why vegetarians and particularly vegans are at greater risk for deficiency and ought to take a dietary supplement which contains B12. Even though there’s absolutely no upper limit for B12, it’s useless to supplement if you don’t have a lack.

Blood levels <200 pg/mL are generally considered paralyzed while >400 pg/mL are sufficient. Between this variety, you might want to think about supplementation. Dosing will vary depending on degree of lack, but is often 1-2 mg per day. Sometimes mega-dose injections each month are required, based on if there is a severe lack or how the person responds to supplementation.

Exactly what does vitamin B12 do?

Vitamin B12 plays a number of roles in our bodies:

  1. It’s necessary for the metabolism of amino acids and fatty acids
  2. It’s necessary for DNA synthesis
  3. It helps adrenal hormones (ie serotonin and dopamine)
  4. It’s essential for cardiovascular function

Getting enough Vitamin B12 in your diet plan is just 1 piece of this image. The B12 needs to be absorbed into the body, then traveling to perform its work, after it has been ingested. Vitamin B12 requires something called “intrinsic variable” (a protein secreted by specific cells in the stomach) in order to be absorbed from the lumen of the gut to the body. Some people don’t make as much intrinsic factor, and generally speaking, as we age, we make less and less, which can be a reason why the older are at greater risk for B12 deficiency, too.

Additionally, (a first line medication commonly used in diabetes therapy), is among the many medications that interferes using absorption of Vitamin B12. It has been projected that 10-30% of people who take metformin might not be able to absorb Vitamin B12. Another study demonstrated that 75% of metformin users were deficient. If you & rsquo; re taking metformin, then you’re at greater risk for B12 deficiency — whether the scope is 10% or 75%, it & rsquo; s still something to be concerned about.

Interestingly, it also seems to be true that B12 deficiency may hyperglycemia (elevated blood glucose levels) therefore there might be a small cyclical relationship between the two.

Among those complications of type 2 diabetes is neuropathy (numbness/pain that often first appears in the hands and feet). Neuropathy is experienced by roughly 30 percent of people with diabetes. Deficiency of B12 is associated with neuropathy as well and it can be difficult to tell if both might be contributing or which might be causing the symptoms.

People who have experienced bariatric surgery are at elevated risk for deficiency also, since their absorptive area has been reduced and the portion of the stomach that secreted intrinsic factor might be eliminated or destroyed.

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Indications of Vitamin B12 Deficiency

Early signs of Vitamin B12 deficiency may contain:

  • Tiredness
  • Weakness
  • Loss of appetite
  • Constipation
  • *B12 deficiency is also curable or without symptoms, particularly in early phases

Vitamin B12 deficiency may eventually lead to something called “pernicious anemia”– in which the body can not make enough red blood cells or supply them with oxygen.

Indicators of pernicious anemia contain:

  • Headache
  • Fatigue
  • Pale skin
  • Chest pain
  • Dizziness
  • Paresthesia (tingling in arms, arms, feet etc)

If left untreated, Long-term B12 deficiency can lead to:

  • Permanent brain and nerve damage
  • Memory Loss
  • Dementia
  • Immobility

Diagnosing Vitamin B12 Deficiency

Discuss your symptoms with your doctor and ask test your levels if you think you might have B12 deficiency. There is a really simple blood test and therapy is as easy as doses.

There are lots of options for supplementing. Cosmetic pills or sublingual (means ‘beneath the tongue’-RRB- options are available over the counter. Frequently, if intrinsic factor is lacking, periodic B12 injections are treated. These shots are given to the muscle and are powerful. This would need to be performed in your doctor&rsquo.

If you’re a vegetarian or vegan, over age 50, have any medical problems with absorption (like any sort of gut surgery or illness), or simply take metformin, then you’re at much greater risk and should be analyzed frequently.

Top sources of Dietary Vitamin B12

  • Liver
  • Clams
  • Caviar
  • Fish — mackerel, herring, salmon, tuna, cod, trout
  • Spicy
  • Organ meats — kidney, heart, giblets, brains
  • Eggs
  • All meats and poultry

Contain in your intake of B12 and your diet ought to be sufficient. If you’re a vegetarian or particularly a vegan, it’s highly recommended you choose a supplement.

Additionally, there are other food items which have been fortified with B12 for example: nutritional yeast, breakfast cereals, breads and at times tofu — but oftentimes, these are foods that we wouldn’t always advocate for a low-carb T2 diabetic diet. Since they’re a far better choice, adhere to the natural food resources.

Just know if you’re deficient in vitamin B12, it is unlikely you will be able to correct the problem through food but will need to include a supplemental kind.

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